New research reveals that people who stop using popular slimming jabs like Mounjaro or Wegovy may regain shed pounds much more quickly than those who halt traditional lifestyle regimens.
Findings released in a leading health publication demonstrates that while overweight individuals often shed substantial amounts of their total mass while using the jabs, the weight is regained at an average rate of nearly a kilo each month once they quit.
"People purchasing such drugs must be cognizant of the potential of fast weight regain when the medication concludes," warns lead investigator Dr. Susan Jebb.
That rate of recovery suggests a return to starting weight in about 18 months.
Comparing Therapies
The research, which reviewed 37 of trials involving thousands of patients, compared the effects of GLP-1 agonists with older methods.
Scientists point out that individuals who shed pounds through diet and exercise generally see a less rapid creep back—perhaps 0.1 kg a month—after stopping.
The Reason for the Fast Rebound
Experts believe the way of the jabs is key to understanding the accelerated regain.
GLP-1 drugs copy a body's own chemical called GLP-1, which helps regulate feelings of fullness.
"Sustained high doses of the hormone concentrations several times higher than normal could lead to the system to produce less of its own natural hormone, and could lessen sensitivity to its effects," explained Dr. Adam Collins, a dietetics researcher.
"Stopping of this hormone supplement leads to hunger is uncontrolled, making overeating far more likely."
A Chronic Disease?
Health authorities advise the jabs for individuals with obesity-related medical conditions, alongside recommended diet and exercise modifications.
Professionals argue that, due to the high risk of relapse, the therapy is often long-term.
This view is supported by drug manufacturers, who note that the results "highlight the chronic character of excess weight," akin to managing conditions like high blood pressure.
User Accounts
Users who have discontinued the medication explain a powerful resurgence of cravings.
"It was like a switch flipping and you're instantly ravenous," recalled a patient.
The struggle is exacerbated if patients have not established permanent lifestyle or habit modifications during treatment.
Widespread Use
Figures suggest that a significant number of adults in the UK have used weight-loss jabs in the past year, with desire continuing to grow.
- Adoption is greater among females compared to men.
- The 40s and 50s demographic shows the greatest level of interest.
- A large proportion access the medications through private healthcare rather than public health services.
In conclusion, clinicians emphasize that while these medications are powerful agents for weight loss, they are not a permanent cure and maintained weight loss likely depends on combined behavioural support.
